More than 10,000 liters of non-sterile air pass through our lungs each day. Although most pathogens are filtered out in the upper respiratory tract, evidence suggests that some bacteria make their way into the alveoli where oxygen and carbon dioxide are exchanged in the lungs.
Read More
Sickle cell disease (SCD) is a group of inherited disorders caused by mutations in the hemoglobin gene. Hemoglobin is responsible for carrying oxygen to cells throughout the body.
Read More
As the COVID-19 pandemic progresses, the need to develop new vaccines and therapeutics intensifies. Animal models of infection play important roles in such discoveries, with mice being the most widely
Read More
Alzheimer’s disease (AD) is the most common cause of dementia worldwide, with the prevalence continuing to grow in part because of an aging world population. This neurodegenerative disease is characte
Read More
Dr. Julie Blander’s group at the School of Medicine at Mount Sinai have discovered that during an infection that causes the apoptosis of infected cells, CD4+ T cells with specificity to self-antigens
Read More
Nicholas J. Leeper’s group at the Stanford University School of Medicine have discovered that the signal that tumor cells display on their surfaces to protect themselves from being cleared by the immu
Read More
It is known that ILCs in the small intestine play a protective role against several mucosal bacterial infections including Yersinia enterocolitica (YE) infection.
Read More
Drs. Katelyn Byrne and Robert Vonderheide from the University of Pennsylvania have discovered that CD40 stimulation along with chemotherapy causes T cell-dependent destruction of pancreatic ductal ade
Read More