Immunoprophylactic and immunotherapeutic control of hormone receptor-positive breast cancer

IL-20 antagonist suppresses PD-L1 expression and prolongs survival in pancreatic cancer models

Team-Building Adventure: Upper Valley Land Trust Group Volunteering

𝘐𝘯𝘝𝘪𝘷𝘰MAb anti-mouse NKG2AB6 (Clone 16A11)

Decidual NK Cells Transfer Granulysin to Selectively Kill Bacteria in Trophoblasts

Type I IFNs and CD8 T cells increase intestinal barrier permeability after chronic viral infection

The Bio X Cell Fund Supports Disaster Relief

IκBα Nuclear Export Enables 4-1BB–Induced cRel Activation and IL-2 Production to Promote CD8 T Cell Immunity

𝙄𝙣𝙑𝙞𝙫𝙤MAb anti-human CD220 / Insulin Receptor (Clone IR 83-22)

The Gut Microbiome Links Stress to Sickle Cell Crisis

Intestinal microbiota-derived short-chain fatty acids regulation of immune cell IL-22 production and gut immunity

Monocyte-derived dendritic cells link localized secretory IgA deficiency to adaptive immune activation in COPD

Bio X Cell Supports Educational Resources Throughout the Upper Valley

Enhancing mucosal immunity by transient microbiota depletion

Chronic activation of 4-1BB signaling induces granuloma development in tumor-draining lymph nodes that is detrimental to subsequent CD8+ T cell responses

MAb anti-mouse CD96 Clone 3.3

Bio X Cell Supports Community Days at YMCA Camp Coniston

Employee-driven Philanthropy Fund

TREM2 Modulation Remodels the Tumor Myeloid Landscape Enhancing Anti-PD-1 Immunotherapy

Bio X Cell Supports School Pals Program

Manganese is critical for antitumor immune responses via cGAS-STING and improves the efficacy of clinical immunotherapy

Blockade of the AHR restricts a Treg-macrophage suppressive axis induced by L-Kynurenine

September Update

Supporting Visions for Creative Housing Solutions

A novel model of COVID-19 Pathogenesis and Treatment

Bio X Cell Joins Global Fight to Defeat COVID-19

Serum HBsAg clearance has minimal impact on CD8+ T cell responses in mouse models of HBV infection

COVER Home Repair - Community Participation Program

Anti-mouse PD-1 (CD279) Clone 29F.1A12

PD-1 pathway regulates ILC2 metabolism and PD-1 agonist treatment ameliorates airway hyperreactivity

MAb anti-human MUC1 (CD227) Clone C595 (NCRC48)

Supporting the American Red Cross with COVID-19 Antibody Testing

Anti-mouse CD4 (Clone GK1.5)

Tissue-resident memory Th17 cells maintain stable fungal commensalism in the oral mucosa

Paddles UP!

Anti-mouse Ly6G/Ly6C (Gr-1) (Clone RB6-8C5)

Tissue-resident memory T cell reactivation by diverse antigen-presenting cells imparts distinct functional responses

Mouse CD163 deficiency strongly enhances experimental collagen-induced arthritis

Korean Society for Stem Cell Research

Opera North Summerfest 2020

Microglia Require CD4 T Cells to Complete the Fetal-to-Adult Transition

Sullivan County Oral Health Collaborative

In vivo microscopy reveals macrophage polarization locally promotes coherent microtubule dynamics in migrating cancer cells

A novel model of apoE4 toxicity in Alzheimer’s disease

Imaging resident and recruited macrophage contribution to Wallerian degeneration

New Hampshire Gives

Team building at its finest!

Having fun while making a difference!

August Update

Vermont Foodbank

Impacts of combining anti-PD-L1 immunotherapy and radiotherapy on the tumour immune microenvironment in a murine prostate cancer model

Upper Valley Humane Society

Requirements for the differentiation of innate T-bethigh memory-phenotype CD4+ T lymphocytes under steady state

Welcome Wolcavi Biotech!

Persistent Zika Virus Clinical Susceptibility despite Reduced Viral Burden in Mice with Expanded Virus-Specific CD8+ T Cells Primed by Recombinant Listeria monocytogenes

Oncolytic virus-derived type I interferon restricts CAR T cell therapy

Brg1 restrains the pro-inflammatory properties of ILC3s and modulates intestinal immunity

MAb anti-human MAGEC2 (CT10) (Clone LX-CT10.5)

Willing Hands

July Update

Donor bone-marrow CXCR4+ Foxp3+ T-regulatory cells are essential for costimulation blockade-induced long-term survival of murine limb transplants

MAb anti-mouse NKG2D (CD314) (Clone CX5)

Transcriptomics and proteomics reveal a cooperation between interferon and T-helper 17 cells in neuromyelitis optica

MYC functions as a switch for natural killer cell-mediated immune surveillance of lymphoid malignancies

Activation of JUN in fibroblasts promotes pro-fibrotic programme and modulates protective immunity

Montshire Museum

Listen Community Services

Chemotherapy-induced ileal crypt apoptosis and the ileal microbiome shape immunosurveillance and prognosis of proximal colon cancer

Contrast-enhanced ultrasound with sub-micron sized contrast agents detects insulitis in mouse models of type1 diabetes

June Update

Carter Community Building Association

Anti-mouse CTLA-4 (CD152)

Microbiota-derived short-chain fatty acids limit the anti-tumor effect of CTLA-4 blockade

Systemic short chain fatty acids limit antitumor effect of CTLA-4 blockade in hosts with cancer

Effective combinatorial immunotherapy for penile squamous cell carcinoma

MAb anti-mouse/human/rat LRP1 (CD91) (Clone: 11H4)

Deubiquitination of NLRP6 inflammasome by Cyld critically regulates intestinal inflammation

Neutrophil extracellular traps released by neutrophils impair revascularization and vascular remodeling after stroke

anlotinib alters tumor immune microenvironment by downregulating PD-L1 expression on vascular endothelial cells

Hepatocyte mitochondria-derived danger signals directly activate hepatic stellate cells and drive progression of liver fibrosis

Our Community

Ly6cLo non-classical monocytes promote resolution of rhesus rotavirus-mediated perinatal hepatic inflammation

May Update

Getting Creative with Social Distancing

MAb anti-mouse TIGIT

Blood-stage malaria parasites manipulate host innate immune responses through the induction of sFGL2

Collagen-binding IL-12 enhances tumour inflammation and drives the complete remission of established immunologically cold mouse tumours

Bio X Cell Opens New Doors

Product Highlights

April Update

TIGIT limits immune pathology during viral infection

FGL-1 is a major inhibitory receptor of LAG-3 and its blockade can potentiate anti-tumor T cell responses

MAb anti-mouse FGL-1 (Clone: 177R4)

Bio X Cell COVID-19 Update

March Update

MAb anti-rat/mouse CD71 (TfR1) (Clone: OX-26)

MAb anti-mouse CD69 (Clone: CD69.2.2)

February News

Targeting sphingolipid metabolism enhances cancer immunotherapy

Supporting our Chinese Partners Fighting the Corona Virus

Team Building with Bio X Cell

An Inside Look at Our Future Space

Life Science Exhibits - University of Florida and University of South Florida

MAb anti-mouse CD71 (TfR1) (Clone: 8D3)

January News

History of Bio X Cell

Top Ten Antibodies in 2019

Hartford Parks & Recreation

Skin resident neutrophils protect against MRSA infection

Tour of Asia

MAb anti-mouse CD28 (Clone: D665)

November News

Targeted CD103+ CD8 T cell depletion prolongs the survival of diabetic mice

MAb anti-human IL-9 (Clone: MH9A4)

The Korean Association of Immunologist International Meeting 2019

International Union of Immunological Societies (IUIS)

October News

Boston FOCIS 2019 Annual Meeting

Yale Immunobiology Retreat 2019

Optimizing anti-4-1BB agonistic antibodies for cancer immunotherapy

September News

Discover if IL-27 plays a role in your research

Fighting cancer with antibodies and philanthropy

Longwood Medical BioResearch Product Faire

Prouty 2019

Does type I collagen play a role in your research?

Just. Pure. Antibodies.and July News

University of Pittsburg BioResearch Product Faire

11th Annual Block Party Supporting Norris Cotton Cancer Center

Does TL1A-DR3 signaling play a role in your research?

June's Latest and Greatest

Prophylactic treatment with antagonistic anti-TNFα antibodies may improve outcomes of anti-PD-1 and anti-CTLA-4 combination cancer immunotherapy

Does SIRPα play a role in your research?

Cedarlane Life Science and Medical Lab Expo

Immunology 2019

Mayday, Spring has Sprung at Bio X Cell

Korean Association of Immunologists

InVivoMAb anti-mouse NKG2A/C/E

Spring into April with our Latest and Greatest!

Welcome Cell Zion

AACR 2019

Deplete neutrophils in mice with InVivoMAb anti-mouse

Activation of ILC2 expressed GITR ameliorates type 2 diabetes

March into News, Research Highlights, and Savings with Bio X Cell

The FasL and the Furious - Introducing anti-mouse Fas ligand (CD178)

Melanoma tumors use IFNγ mutations to fight anti-CTLA-4 immunotherapy

How do I decide which anti-mouse PD-1 antibody is best for me?

Oxygen sensing by T cells facilitates the establishment of cancer metastasis in the lung

Bio X Cell's Top 20

Happy Holidays!

VPR's Membership Drive

A Novel Immune Checkpoint Inhibitor Anti-NKG2A Antibody Promotes Anti-Tumor Immunity by Unleashing Both T and NK Cells

Microbial Infection Induces Autoimmunity

Happy Thanksgiving!

What's your favorite pie?

Anti-CD47 antibodies counter cardiovascular disease

We Walk Brussels

Pumpkin Carving at Bio X Cell

Blocking messages carried through brain lymphatic vessels curbs the development of multiple sclerosis

2018 Nobel Prize for Medicine

Naïve T cells switch to one-carbon metabolism upon activation

Microbiota-derived short-chain fatty acids promote Th1 cell IL-10 production to maintain intestinal homeostasis

LIGHT-HVEM signaling protects against enteric bacterial infection

The program for central memory T cell generation is preserved intrinsically in CD8 T cells.

TIGIT blockade prevents NK cell exhaustion and elicits potent anti-tumor immunity

Prouty 2018

Regulatory T cells use lymphotoxin beta receptor to migrate from tissues to lymph nodes

CD40 stimulation drives T cell immunity in cancer

AAI 2018

AACR 2018