Employee-driven Philanthropy Fund

Posted in Bio X Cell Charitable Fund, Featured

      Making a difference "We are a team driven by the idea of giving back to our community and bettering the lives of those in need around us. Making a difference in our community gives us greater meaning in the work that we do at Bio X Cell and ful...
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TIGIT limits immune pathology during viral infection

Posted in Research Highlights, Featured

TIGIT limits immune pathology during viral infection Immune checkpoint proteins play a fundamental role in regulating T cell responses during viral infections. On one hand, they need to promote T cell functions in order to clear the virus. On the other hand, they need to restrict T cell activity to prevent immunopathology. Understanding the effects of these checkpoint inhibitors could result in the development of novel therapies to treat viral infections.
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FGL-1 is a major inhibitory receptor of LAG-3 and its blockade can potentiate anti-tumor T cell responses

Posted in Research Highlights, Featured

  FGL-1 is a major inhibitory receptor of LAG-3 and its blockade can potentiate anti-tumor T cell responses   Lymphocyte-activation gene 3 (LAG-3) is a receptor that negatively regulates the proliferation, activation, and effector function of T cells...
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MAb anti-rat/mouse CD71 (TfR1) (Clone: OX-26)

Posted in Product Highlights, Featured

Product References Shop anti-rat/mouse CD71     InVivoMAb anti-rat/mouse CD71 (TfR1) Useful for targeted drug delivery to the brain The OX-26 monoclonal antibody reacts with rat CD71 also known as transferrin receptor protein 1 (TfR1). The antibody i...
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MAb anti-mouse CD69 (Clone: CD69.2.2)

Posted in Product Highlights, Featured

  Product References Shop InVivoMAb anti-mouse CD69     InVivoMAb anti-mouse CD69 The CD69.2.2 monoclonal antibody reacts with mouse CD69, an 85 kDa type II C-type lectin. CD69 expression is rapidly induced upon cell activation in all leukocytes. CD6...
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Targeting sphingolipid metabolism enhances cancer immunotherapy

Posted in Research Highlights, Featured

  Targeting sphingolipid metabolism enhances cancer immunotherapy   CTLA-4 and PD-1 based immunotherapies have demonstrated significant clinical efficacy in melanoma patients, but many patients remain non-responsive and relapse is common. To try and ...
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MAb anti-mouse CD71 (TfR1) (Clone: 8D3)

Posted in Product Highlights, Featured

Product References Shop anti-mouse CD71 (TfR1)
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Top Ten Antibodies in 2019

Posted in Product Highlights, Featured

Bio X Cell's Top Ten Antibodies in 2019
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Skin resident neutrophils protect against MRSA infection

Posted in Research Highlights, Featured

Skin resident neutrophils protect against MRSA infection   Staphylococcus aureus is a common bacterium carried on the skin of up to 50% of the population. Carriage of S. aureus is typically asymptomatic however, it is responsible for 76% of all skin ...
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MAb anti-mouse CD28 (Clone: D665)

Posted in Product Highlights, Featured

Learn how other researchers have used the anti-mouse CD28 antibody. Product References Shop anti-mouse CD28     InVivoMAb anti-mouse CD28 The D665 monoclonal antibody reacts with mouse CD28, a 45 kDa costimulatory receptor and a member of the Ig supe...
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