Bio X Cell Blog

Type I IFNs and CD8 T cells increase intestinal barrier permeability after chronic viral infection

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IκBα Nuclear Export Enables 4-1BB–Induced cRel Activation and IL-2 Production to Promote CD8 T Cell Immunity

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Intestinal microbiota-derived short-chain fatty acids regulation of immune cell IL-22 production and gut immunity

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Bio X Cell antibodies were used to study the roles of microbiota-derived short-chain fatty acids (SCFAs) in inducing IL-22 production in CD4+ T cells and Innate lymphoid cells (ILCs) to maintain intestinal homeostasis.
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Monocyte-derived dendritic cells link localized secretory IgA deficiency to adaptive immune activation in COPD

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Mice were injected intraperitoneally with anti-CD8 (clone 2.4, BioXCell BE0061), anti-CD4 (clone GK1.5, BioXCell BE0003-1), or rat IgG2b isotype control (clone LTF-2, BioXCell BE0090)
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Enhancing mucosal immunity by transient microbiota depletion

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Chronic activation of 4-1BB signaling induces granuloma development in tumor-draining lymph nodes that is detrimental to subsequent CD8+ T cell responses

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TREM2 Modulation Remodels the Tumor Myeloid Landscape Enhancing Anti-PD-1 Immunotherapy

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Manganese is critical for antitumor immune responses via cGAS-STING and improves the efficacy of clinical immunotherapy

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Blockade of the AHR restricts a Treg-macrophage suppressive axis induced by L-Kynurenine

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Serum HBsAg clearance has minimal impact on CD8+ T cell responses in mouse models of HBV infection

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For more than 20 years, scientists have trusted Bio X Cell as their go-to source for in vivo functional grade antibodies. We take this responsibility to heart and have always focused our efforts on one goal: producing the highest-quality antibodies with the best value possible. Our unwavering commitment to scientists has inspired us to create and optimize a proprietary in vivo antibody manufacturing method with significant advantages which directly benefit our customers.

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