Type I IFNs and CD8 T cells increase intestinal barrier permeability after chronic viral infection

Posted in Research Highlights

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The Bio X Cell Fund Supports Disaster Relief

Posted in Bio X Cell Charitable Fund

The Bio X Cell Fund is proud to support these organizations and the work they are doing to help rebuild and recover from natural disasters.
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IκBα Nuclear Export Enables 4-1BB–Induced cRel Activation and IL-2 Production to Promote CD8 T Cell Immunity

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𝙄𝙣𝙑𝙞𝙫𝙤MAb anti-human CD220 / Insulin Receptor (Clone IR 83-22)

Posted in New Products

Introducing 𝘐𝘯𝘝𝘪𝘷𝘰MAb anti-human CD220 (Insulin Receptor) Clone IR 83-22 for western blot applications.
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The Gut Microbiome Links Stress to Sickle Cell Crisis

Posted in Research Summary

Sickle cell disease (SCD) is a group of inherited disorders caused by mutations in the hemoglobin gene. Hemoglobin is responsible for carrying oxygen to cells throughout the body.
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Intestinal microbiota-derived short-chain fatty acids regulation of immune cell IL-22 production and gut immunity

Posted in Research Highlights

Bio X Cell antibodies were used to study the roles of microbiota-derived short-chain fatty acids (SCFAs) in inducing IL-22 production in CD4+ T cells and Innate lymphoid cells (ILCs) to maintain intestinal homeostasis.
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Monocyte-derived dendritic cells link localized secretory IgA deficiency to adaptive immune activation in COPD

Posted in Research Highlights

Mice were injected intraperitoneally with anti-CD8 (clone 2.4, BioXCell BE0061), anti-CD4 (clone GK1.5, BioXCell BE0003-1), or rat IgG2b isotype control (clone LTF-2, BioXCell BE0090)
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Bio X Cell Supports Educational Resources Throughout the Upper Valley

Posted in Bio X Cell Charitable Fund

These organizations, throughout the Upper Valley, are working hard to ensure that all children live joyful, healthy, and active lives.
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Enhancing mucosal immunity by transient microbiota depletion

Posted in Research Highlights

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Chronic activation of 4-1BB signaling induces granuloma development in tumor-draining lymph nodes that is detrimental to subsequent CD8+ T cell responses

Posted in Research Highlights

Bio X Cell Reference Spotlight
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