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The 16A11 monoclonal antibody reacts with NKG2A from C57BL/6 mice, the antibody does not react with BALB/c or 129 mouse strains. NKG2A, also known as CD159a is a type II transmembrane glycoprotein which belongs to the killer cell lectin-like receptor (KLR) family. NKG2A is expressed on NK cells, NKT cells, and activated CD8 T cells. NKG2A forms a disulfide-bonded heterodimer with CD94 that can bind to non-classical MHC class I antigen Qa-1 on target cells and inhibit NK cell activation.
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This antibody is useful for:
Flow cytometry
Bio X Cell antibodies are specifically formulated for in vivo use and feature:
95% purity
Ultra-low endotoxin levels
Preservative, stabilizer, and carrier protein-free
Recommended isotype control and dilution buffer:
InVivoMAb mouse IgG1 isotype control, unknown specificity
InVivoPure pH 7.0 Dilution Buffer